Speaker
Description
Pelvic Congestion Syndrome (PCS) is characterized by venous insufficiency in ovarian and pelvic veins, leading to blood reflux and chronic pelvic pain. Current endovascular treatments rely on the deployment of multiple metallic coils, whose crimped length necessitates repeated implantation to effectively occlude varicose branches and redirect flow. In this study, we propose a biodegradable porous device as an alternative strategy to achieve flow redistribution while enabling complete resorption. An integrated approach combining experimental testing, theoretical analysis, and computational simulations was developed to determine optimal porosity and device dimensions. Controlled experiments were conducted to quantify pressure drop as a function of flow rate across porous structures. Complementary theoretical models were used to assess flow redistribution at vascular bifurcations, accounting for variations in branch diameters. The combined insights from simplified theory, numerical simulations using Computer Fluid Dynamics (CFD), and experimental validation enabled the identification of key design parameters, including porosity and device length, required to efficiently redirect flow away from varicose veins. This work provides a foundation for the development of next-generation biodegradable embolization devices with improved efficacy and reduced need for multiple implants.
| Topic Area | Design Optimization, Additive Manufacturing Technologies & Applications |
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