Speaker
Yvo Pokern
(University College London)
Description
Electron-nuclear double resonance (ENDOR) spectroscopy is a sophisticated method to indirectly measure intra-molecular distances and orientations for complex biomolecules. Experimental limitations mean that the complex microwave echo signal, recorded as a real (in-phase) and imaginary (in-quadrature) component for each of the different frequencies used to excite the system, has an unidentifiable global phase and magnitude factor. Quotienting this out leads to the natural parameter space on which to perform inference: complex projective space. This work presents estimation methodology, parametric testing and nonparametric estimation based on ENDOR measurements including numerical and first theoretical results on consistency.
Author
Yvo Pokern
(University College London)